About The Event
Graphene and Post-Graphene Materials: Lessons from the Graphene Flagship
The innate arm of the immune system represents the first line of cellular defense against foreign intrusion. Understanding the interactions of graphene and other two-dimensional (2D) materials with the immune system is of key importance for the safe and sustainable development and use of this emerging class of advanced materials. This seminar will provide examples of studies conducted in the EU-funded Graphene Flagship on the interactions of graphene family materials such as graphene oxide (GO) with the immune system, focusing on macrophages and neutrophils. Furthermore, we will discuss the biological impact of post-graphene materials including transition metal dichalcogenides (TMDs) and 2D transition metal carbides and nitrides, especially the “classical” titanium carbide MXenes, with particular reference to inflammation, a protective response against pathogens and other harmful stimuli. We will discuss the activation of inflammasomes, innate immune receptors/sensors that play a key role in regulating inflammation and secretion of the proinflammatory mediator, interleukin (IL)-1β
